KPV (Lys-Pro-Val) research peptide — wholesale supply

For research use only · Not for human consumption · Not for veterinary use. This product is supplied for in-vitro research, analytical method development, and laboratory reference standard use only. Not approved as a drug, medical device, or diagnostic agent. Not for human or veterinary administration. Buyer is responsible for end-use classification in the destination jurisdiction.

Overview

KPV is the C-terminal tripeptide of alpha-melanocyte-stimulating hormone, a fragment of three amino acids with the sequence Lys-Pro-Val. It has a molecular formula of C₁₆H₃₀N₄O₄ and a molecular weight of 342.43 g/mol as the free peptide, and the CAS number is 67727-97-3. It is one of the shortest compounds in the SPK Pharma catalogue and one of the simplest to work with — a linear tripeptide with no secondary structure and no cysteine residue.

KPV is the subject of a substantial research literature on the melanocortin receptor system, where it is used as the minimal pharmacophoric fragment for receptor-binding and antagonist studies. Because it is only three residues, KPV is also a common candidate for conjugation work, for radiolabelling, and as a building block in more elaborate solid-phase synthesis routes.

SPK Pharma India supplies KPV standalone for distributors, contract manufacturers, and academic laboratories. It is also the fourth component of our four-peptide research blend, BPC-157 + TB-500 + GHK-Cu + KPV, where the tripeptide is included for comparative work across the component set. Buyers who require the tripeptide in a single-component lot should order it standalone rather than specifying it out of the blend, because the blend COA reports each component peak by area-percent rather than by absolute mass.

Specifications

Research context

KPV is used in-vitro as the reference fragment for melanocortin receptor pharmacology, where it is applied to map the minimum recognition sequence required at the receptor and to generate labelled and modified analogues for binding and imaging studies. The Lys side chain provides the basic residue that engages the receptor's conserved acidic pocket, and the proline in the middle position is what constrains the backbone conformation.

The tripeptide is also used in work on peptide half-life and protease susceptibility, where it serves as a minimal substrate for exopeptidase panels. Because there is no cysteine and no aromatic residue, KPV is comparatively stable to oxidation, and it does not show the light sensitivity that TB-500 does.

For researchers new to the compound, the reliable analytical reference points are CAS 67727-97-3, the Lys-Pro-Val sequence, the molecular formula C₁₆H₃₀N₄O₄, and the 342.43 g/mol free-peptide molecular weight. If your material is supplied as an acetate salt, the mass will differ and the lot COA will state the salt form explicitly. SPK Pharma India makes no therapeutic, clinical, diagnostic or dosing claims for this product.

Packaging and supply

• 5 mg research vial — for method development, receptor panels and screening. Standard MOQ: 5 vials.
• 10 mg research vial — for repeat assay work and conjugation campaigns. Standard MOQ: 5 vials.
• Bulk pack — on application, for annual supply contracts and recurring orders.

Distributor pricing is available on application. Annual supply contracts with scheduled recurring dispatch are available for repeat buyers. Lead time for in-stock SKUs is typically 5 business days from purchase order confirmation; lead time for scheduled production is typically 4 to 6 weeks.

Quality and documentation

Every lot of KPV ships with a lot-matched Certificate of Analysis documenting identity (mass spectrometry), purity (HPLC with chromatogram), peptide content, counter-ion, appearance, lot number, and synthesis batch reference. A representative sample of every lot is independently verified by a third-party analytical laboratory before release. MSDS is supplied with every shipment. The COA template, the lot-traceability workflow, and the third-party verification scope are documented on the Quality page.

Storage and handling

• Store at -20°C in the original sealed container.
• Protect from light and moisture.
• Allow the sealed container to reach room temperature before opening, to avoid condensation.
• Reconstitute in sterile, low-endotoxin research-grade water or in a mild buffer at the working concentration required by the assay.
• Do not refreeze once reconstituted; aliquot and store at working concentration.
• Gentle swirling dissolves a tripeptide readily; vigorous vortexing is unnecessary.

Shipping

KPV is shipped lyophilized in sealed vials within temperature-validated packaging. International lanes are routed through dedicated life-science logistics partners with cold-chain handling. Standard dispatch is within 5 business days of purchase order confirmation. SPK Pharma India ships to the United States, the European Union, the United Kingdom, Canada, MENA, APAC, and LATAM. Full export documentation, including commercial invoice, packing list, certificate of origin, COA, and MSDS, is included with every shipment. Destination-specific documentation is supported on request.

Compliance

This product is supplied for research use only. It is not a drug, not a finished dosage form, and not approved for human or veterinary administration. SPK Pharma India does not make therapeutic, clinical, diagnostic, or dosing claims for this product. The buyer is responsible for end-use classification in the destination jurisdiction and for ensuring that downstream handling is consistent with research-use-only protocols.

Lead form CTA

To request a wholesale quote for KPV, contact the trade desk with the subject line "KPV wholesale quote" and your company details, expected volume, and destination country. Distributor pricing is available on application. The desk responds within one business day.

Related compounds

• BPC-157 — synthetic gastric-derived pentadecapeptide
• TB-500 (Thymosin Beta-4) — 43-residue actin-binding peptide
• GHK-Cu (Copper Tripeptide-1) — copper-binding repair signal
• SS-31 (Elamipretide) 10 mg — mitochondria-targeted antioxidant peptide
• BPC-157 + TB-500 + GHK-Cu + KPV — four-component research blend